What about side effects? It is completely normal for medication to have side effects; you just need to find the ones with the least side effects if you can. HIV treatments have advanced significantly over the years and some of the more severe side effects are no longer a problem. Most side effects such as nausea, headaches and diarrhoea generally subside within the first few weeks however some may persist. Talking to your doctor will ensure you get the combination right and they will be able to give you some advice for managing your medication. Simple tips such as keeping a diary of any side effects so your doctor can easily see the problems or taking your medication before bed so that you will sleep through the immediate effects can be really effective. Antiretroviral (ARV) can also interfere with other prescribed drugs that you can buy over the counter, herbal remedies or recreational drugs. Think about telling your pharmacist or doctor what other medication or drugs you are taking so that you can access the best HIV treatment.